More Bone. Faster.
HAnano Surface® combines several properties, known to improve osseointegration, in one unique surface modification. The combination of high wettability and optimal surface chemistry with optimized nano-roughness, mediates bioactivity and specific protein adsorption to the implant. These properties regulate cell behavior and influences tissue regeneration by increasing the osteoblast functions, thus building more bone faster.
Adding a New Dimension to Osseointegration
HAnano Surface introduces a new size regime for implant coatings. The nano-thin surface enables newly formed bone to grow directly into the micrometer topography, or roughness, of the implant surface, thus providing mechanical stability.
Compared to traditional coatings, where bone anchors to the coating, HAnano Surface does not act as an interface separating bone from the implant. Furthermore, with the particle based HAnano Surface there is no risk for cracking or delamination. In addition, since the dimensions of the implant are unchanged, there is no need for new drilling procedures or changes in instrument design.
Applications and Industries
HAnano Surface can be used on orthopedic, spinal and dental implants. The surface modification has excellent compatibility with various types of substrates, including metals, ceramics and polymers such as PEEK. HAnano Surface can transform the surface of any implant – regardless of geometry, structure or porosity – to a surface that resembles natural human bone tissue.
Technology and Process
The surface modification with HAnano Surface is based on a wet chemical process. Only off-the-shelf equipment is required and can easily be implemented at existing implant manufacturing lines. For OEMs without in-house manufacturing capabilities, Promimic has established a strategic partnership with Danco Anodizing, a leading supplier of surface treatments to the medical device industry. Danco Anodizing has a fully implemented HAnano Surface production line in their facility in Warsaw, Indiana (US), which is now offered to Promimic’s customers.
The technology behind HAnano Surface is versatile and can be used in many different applications. The surface modification can be used to increase hydrophilicity or bone cell activity on any material that can withstand a short heat treatment.